Methylamine → HCID 14760633、化合物

HRID 704648ノート

反応式

HRID 704648 の反応式
[C:1]1([CH:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[O:8][C:9]2[C:14](=[O:15])[CH:13]=[C:12]([CH2:16][OH:17])O[CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:24][NH2:25]>CO>[C:1]1([CH:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[O:8][C:9]2[C:14](=[O:15])[CH:13]=[C:12]([CH2:16][OH:17])[N:25]([CH3:24])[CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 6329MethylamineHCID 143063875-(benzhydryloxy)-2-(hydroxymethyl)-4H-pyran-4-one

生成物 1

HCID 14760633HCID 14760633、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a solution of 3.035 g of 3-diphenylmethoxy-6-hydroxymethyl-4-pyrone in 20 ml of methanol is added 50 ml of 40% aqueous methylamine solution, and the mixture is stirred for 4 hours. The reaction mixture is condensed under reduced pressure to a volume of 15 ml, and the resulting crystal is collected by filtration, washed with a small amounts of water and ethyl acetate in this sequence, and dried under reduced pressure to give 2.04 g of the title compound.

後処理

  1. customcondensed under reduced pressure to a volume of 15 ml
  2. filtrationthe resulting crystal is collected by filtration
  3. washwashed with a small amounts of water and ethyl acetate in this sequence
  4. customdried under reduced pressure

出典と根拠

ORDレコード
ord-cd77939740b5488a9ea268b82d6ec1e6
出典データセット
uspto-grants-1991_01
特許番号
US04988686

反応ノート

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