化工社化工社 化学情報印刷レポート · 研究参考用
4-Chloro-3-nitrobenzenesulfonamide → 3-chloro-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Chloro-3-nitrobenzenesulfonamide | HCID 7324 | — |
| 反応物 | N,N,N',N'-Tetramethylethylenediamine | HCID 8037 | — |
| 反応物 | Diisopropylethylamine | HCID 81531 | — |
| 反応物 | 4-Methylpiperazin-1-ylamine dihydrochloride hydrate | HCID 198221 | — |
| 反応物 | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| 生成物 | 3-chloro-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide | HCID 67126616 | — |
反応手順
The title compound was prepared by substituting 4-fluoro-3-chlorobenzenesulfonamide for 4-chloro-3-nitrobenzenesulfonamide, (tetrahydro-2H-pyran-4-yl)methanamine for 4-methylpiperazin-1-amine dihydrochloride and Hunig's base for N1,N1,N2,N2-tetramethylethane-1,2-diamine in EXAMPLE 6A.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09174982B2 |
| 出典データセット | uspto-grants-2015_11 |
| ORD ID | ord-0ab115c41266436d864e6e073f2a2dad |
| 出典メモ | uspto-grants-2015_11 |