1-Ethynyl-4-methoxybenzene → 5-(4-Methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole

HRID 707627ノート

反応式

HRID 707627 の反応式
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[CH:5][CH:4]=1)#[CH:2].[CH3:11][O:12][C:13]1[CH:14]=[C:15]([N:23]=[N+:24]=[N-:25])[CH:16]=[C:17]([O:21][CH3:22])[C:18]=1[O:19][CH3:20]>>[CH3:11][O:12][C:13]1[CH:14]=[C:15]([N:23]2[C:1]([C:3]3[CH:8]=[CH:7][C:6]([O:9][CH3:10])=[CH:5][CH:4]=3)=[CH:2][N:25]=[N:24]2)[CH:16]=[C:17]([O:21][CH3:22])[C:18]=1[O:19][CH3:20]

参加物

3

反応物 2

HCID 2510201-Ethynyl-4-methoxybenzeneHCID 59430102HCID 59430102、化合物

生成物 1

HCID 445852705-(4-Methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole

反応条件

温度
80 °C

実験手順

To a scintillation vial was added 4-ethynyl anisole (660 mg.; 5 mmol) and 3,4,5-trimethoxyphenyl azide (1.05 g.; 5 mmol) and the mixture was heated at 80° C. for 24 hours. The crude mixture was purified by column chromatography to give 1-(3,4,5-trimethoxy-phenyl)-5-(4-methoxy-phenyl)-1H-[1,2,3]triazole.

後処理

  1. customThe crude mixture was purified by column chromatography

出典と根拠

ORDレコード
ord-fc400c0b3c7b4d198ae81546e95b4320
出典データセット
uspto-grants-2015_11
特許番号
US09175022B2

反応ノート

読み込み中…