化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Bromide → 4-Pentenoic acid, phenylmethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-Pentenoic acid | HCID 61138 | — |
| 触媒 | Tetrabutylammonium Iodide | HCID 67553 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 4-Pentenoic acid, phenylmethyl ester | HCID 10052035 | — |
反応手順
Benzyl bromide (7.19 g, 42.04 mmol) was added to a solution of 4-pentenoic acid (6) (5.05 g, 50.45 mmol, 1.2 eq.) in acetone (75 ml) at RT under N2. Anhydrous potassium carbonate (29.05 g, 210.19 mmol, 5.0 eq.) and tetrabutylammonium iodide (0.776 g, 2.102 mmol, 0.05 eq.) were added and the resulting suspension was stirred over 2 days. LCMS analysis showed mainly product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09175032B2 |
| 出典データセット | uspto-grants-2015_11 |
| ORD ID | ord-439d5aef3c3846a581ca6f50f0f9aee2 |
| 出典メモ | uspto-grants-2015_11 |