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4-hydroxy-N-(3-iodophenyl)-3-methoxyphenylacetamide → 4-hydroxy-3-methoxy-N-[2-(2-phenylethynyl)phenyl]-phenylacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-hydroxy-N-(3-iodophenyl)-3-methoxyphenylacetamide | HCID 12096660 | — |
| 反応物 | 4-hydroxy-N-(2-iodophenyl)-3-methoxyphenylacetamide | HCID 22019613 | — |
| 生成物 | 4-hydroxy-3-methoxy-N-[2-(2-phenylethynyl)phenyl]-phenylacetamide | HCID 22019673 | — |
反応手順
Instead of Intermediate 1 in Example 36, 4-hydroxy-N-(2-iodophenyl)-3-methoxyphenylacetamide is treated in a similar manner to Example 36 to give the desired compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07084176B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-89b0d7fa5702421e85b242cc98976b63 |
| 出典メモ | uspto-grants-2006_08 |