2,3-Dimethoxy-5-[(1-phenylethyl)sulfanyl]pyridine → 3-Hydroxy-5-[(1-phenylethyl)sulfanyl]pyridin-2(1H)-one

反応式

C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.C[O:18][C:19]1[C:24]([O:25]C)=[CH:23][C:22]([S:27][CH:28]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH3:29])=[CH:21][N:20]=1>>[OH:25][C:24]1[C:19](=[O:18])[NH:20][CH:21]=[C:22]([S:27][CH:28]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH3:29])[CH:23]=1

参加物

反応物 2

HCID 711861842,3-Dimethoxy-5-[(1-phenylethyl)sulfanyl]pyridine2 回

HCID 71187166HCID 71187166、化合物

生成物 1

HCID 711871513-Hydroxy-5-[(1-phenylethyl)sulfanyl]pyridin-2(1H)-one

実験手順

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 1) to from 2,3-dimethoxy-5-[(1-phenylethyl)sulfanyl]pyridine (Intermediate 9).

後処理

customPrepared

出典と根拠

ORDレコード: ord-c6d49995cc5f4296bc1e149bf41526fc
出典データセット: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09180122B2

反応ノート

読み込み中…