2,3-Dimethoxy-5-[(2-methylbenzyl)sulfanyl]pyridine → 3-Hydroxy-5-[(2-methylbenzyl)sulfanyl]pyridin-2(1H)-one

反応式

C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.C[O:18][C:19]1[C:24]([O:25]C)=[CH:23][C:22]([S:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[CH3:35])=[CH:21][N:20]=1>>[OH:25][C:24]1[C:19](=[O:18])[NH:20][CH:21]=[C:22]([S:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[CH3:35])[CH:23]=1

参加物

反応物 2

HCID 711864382,3-Dimethoxy-5-[(2-methylbenzyl)sulfanyl]pyridine2 回

HCID 71187166HCID 71187166、化合物

生成物 1

HCID 711871903-Hydroxy-5-[(2-methylbenzyl)sulfanyl]pyridin-2(1H)-one

実験手順

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 1) from 2,3-dimethoxy-5-[(2-methylbenzyl)sulfanyl]pyridine (Intermediate 12).

後処理

customPrepared

出典と根拠

ORDレコード: ord-b21af6a848714a88a004e912bdc7fd52
出典データセット: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09180122B2

反応ノート

読み込み中…