関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester | HCID 70670 | — |
| 反応物 | 2-Fluoro-3-methoxybenzaldehyde | HCID 3774463 | — |
| 生成物 | Ethyl (2-fluoro-3-methoxyphenyl)acrylate | HCID 131733905 | — |
反応手順
To a solution of 2-fluoro-3-methoxybenzaldehyde (2.00 g) in toluene (50 mL) was added ethyl (triphenylphosphoranylidene)acetate (4.50 g), and the mixture was stirred at 110° C. for 4 hr. The reaction mixture was concentrated, and the residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (2.50 g) as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09181186B2 |
|---|
| 出典データセット | uspto-grants-2015_11 |
|---|
| ORD ID | ord-ec62c66f8bda401e941f3729936ef69c |
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| 出典メモ | uspto-grants-2015_11 |
|---|
