3-(4-(Trifluoromethyl)phenyl)propionic Acid → HCID 178506154、化合物

関与物質

役割	名称	HCID	仕込み量
反応物	3-(4-(Trifluoromethyl)phenyl)propionic Acid	HCID 3588736	—
反応物	1H-benzimidazole-5-carbohydrazide	HCID 16637119	—
生成物	HCID 178506154	HCID 178506154	—

反応手順

The compound was synthesized starting from benzimidazol-5-carbohydrazide (176 mg, 1 mmol) and 3-(4-trifluoromethylphenyl)propionic acid (218 mg; 1 mmol) as described in method 2; yield: 0.043 mg (12.0%); MS m/z: 359.2 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 3.21-3.25 (m, 2H); 3.31-3.35 (m, 2H); 7.54-7.56 (m, 2H); 7.64-7.67 (m, 2H); 7.86 (d, 1H, 3J=8.7 Hz); 7.92 (dd, 1H, 4J=1.7 Hz, 3J=8.7 Hz); 8.24 (d, 1H, 4J=1.7 Hz); 8.87 (s, 1H); HPLC (METHOD [A]): rt 13.82 min (95.9%)

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US09181233B2
出典データセット	uspto-grants-2015_11
ORD ID	ord-dcd70e142719437f82c358a49f31ea33
出典メモ	uspto-grants-2015_11