化工社化工社 化学情報印刷レポート · 研究参考用
P-Coumaric Acid → HCID 178511829、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | P-Coumaric Acid | HCID 637542 | — |
| 反応物 | Sitagliptin | HCID 4369359 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | HCID 178511829 | HCID 178511829 | — |
反応手順
Sitagliptin free base (0.25 gms) and coumaric acid (0.10 gms) were dissolved in Isopropanol (4 ml) at 60° C. to 65° C. and the resultant solution left for slow solvent evaporation at room temperature for 48 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 4 hours to obtain the title compound. Yield: 0.14 gms.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09181256B2 |
| 出典データセット | uspto-grants-2015_11 |
| ORD ID | ord-073ae264f1aa48408fde797398611266 |
| 出典メモ | uspto-grants-2015_11 |