4-Bromo-6-methoxy-2-methylquinoline → 4-Bromo-2-methyl-quinolin-6-ol

反応式

CC1C=C(C(F)(F)F)C2C(=CC=C(O)C=2)N=1.[Br:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[C:25]([O:28]C)[CH:26]=2)[N:21]=[C:20]([CH3:30])[CH:19]=1>>[Br:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[C:25]([OH:28])[CH:26]=2)[N:21]=[C:20]([CH3:30])[CH:19]=1

参加物

反応物 2

HCID 170400724-Bromo-6-methoxy-2-methylquinoline

HCID 669259052-Methyl-4-trifluoromethyl-quinolin-6-ol

生成物 1

HCID 669264634-Bromo-2-methyl-quinolin-6-ol

実験手順

Synthesized as per 2-Methyl-4-trifluoromethyl-quinolin-6-ol using 4-Bromo-6-methoxy-2-methyl-quinoline as starting material. ESI-MS(M+H+): 238.00/240.00.

出典と根拠

ORDレコード: ord-b9d4a4274b4e44458ff30352ae922536
出典データセット: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09186367B2

反応ノート

読み込み中…