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HRID 716008作成日：2026年10月26日
Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → (E)-methyl 4-(2-nitrophenyl)but-2-enoate
https://huagongshe.com/reaction/716008
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester | HCID 17453 | — |
| 反応物 | 2-Nitrobenzeneacetaldehyde | HCID 10844764 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | (E)-methyl 4-(2-nitrophenyl)but-2-enoate | HCID 15264372 | — |
| 生成物 | (E)-Methyl 4-(2-nitrophenyl)but-3-enoate | HCID 20269937 | — |
反応手順
A mixture of 2-(2-nitrophenyl)acetaldehyde (760 mg, 4.6 mmol) and methoxylcarbonylmethylenetriphenylphosphorane (1.5 g, 4.6 mmol) in toluene (10 mL) was heated at 110° C. for 3 hours. The crude material was purified by silica gel column chromatography eluting with hexanes and ethyl acetate (2:1) to afford the title compound along with (E)-methyl 4-(2-nitrophenyl)but-2-enoate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US09187483B2 |
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| 出典データセット | uspto-grants-2015_11 |
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| ORD ID | ord-bde7d12ffb644ed1aa14dc738b1a44a5 |
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| 出典メモ | uspto-grants-2015_11 |
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