化工社化工社 化学情報印刷レポート · 研究参考用
3-(4-Fluorophenoxy)propionic acid → Dimethyl 2-(3-(4-fluorophenoxy)propanamido)malonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(4-Fluorophenoxy)propionic acid | HCID 74099 | — |
| 反応物 | Dimethyl aminomalonate hydrochloride | HCID 437601 | — |
| 生成物 | Dimethyl 2-(3-(4-fluorophenoxy)propanamido)malonate | HCID 50941576 | 80% |
反応手順
This compound was synthesized from dimethyl aminomalonate according to the procedure for the preparation of example 2 using 3-(4-fluorophenoxy)propionic acid. The crude residue was purified by flash chromatography on silica (CH2Cl2/MeOH 50:1) to yield the title compound as a white solid (80%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09193741B2 |
| 出典データセット | uspto-grants-2015_11 |
| ORD ID | ord-8cb18608e0f94394af6f322bdd1a3d92 |
| 出典メモ | uspto-grants-2015_11 |