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Dimethylformamide → 7-Bromo-12,12-dimethyl-10-phenyl-10,12-dihydroindeno[2,1-b]carbazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | 12,12-Dimethyl-10-phenyl-10,12-dihydroindeno[2,1-b]carbazole | HCID 86685014 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 7-Bromo-12,12-dimethyl-10-phenyl-10,12-dihydroindeno[2,1-b]carbazole | HCID 86685015 | 94.8% |
反応手順
The resulting 12,12-dimethyl-10-phenyl-10,12-dihydroindeno[2,1-b]carbazole (7.5 g) and DMF (53 ml) were added to a reaction vessel. N-bromosuccinimide (3.72 g) was added under ice-cooled conditions, and the mixture was stirred for 9 hours and then left for one night. Water (260 ml) was added, and the mixture was subjected to filtration to obtain a brownish white powder of 7-bromo-12,12-dimethyl-10-phenyl-10,12-dihydroindeno[2,1-b]carbazole (8.67 g; yield 94.6%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09196837B2 |
| 出典データセット | uspto-grants-2015_11 |
| ORD ID | ord-482225d7960242e497efc6bf60ca73fc |
| 出典メモ | uspto-grants-2015_11 |