Acetic Acid → 1-Methoxycarbonyl-2-isopropylidene hydrazine

HRID 71919

反応式

HRID 71919 の反応式
[CH3:1][O:2][C:3]([NH:5][NH2:6])=[O:4].C(O)(=O)C.O.[CH3:12][C:13]([CH3:15])=O>>[CH3:1][O:2][C:3]([NH:5][N:6]=[C:13]([CH3:15])[CH3:12])=[O:4]

参加物

5

反応物 4

HCID 176Acetic AcidHCID 180AcetoneHCID 962WaterHCID 80519Methyl carbazate

生成物 1

HCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine収率 89%

実験手順

Hydrazinecarboxylic acid methyl ester (5.01 g) were dissolved in acetone (28 mL), and acetic acid (0.0636 mL) was added. The reaction mixture was stirred at room temperature for 24 hours. Water (50 mL) was added, and mixture was extracted three times with DCM (50 mL) and evaporated under vacuum, giving N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g, 89%).

後処理

  1. extractionmixture was extracted three times with DCM (50 mL)
  2. customevaporated under vacuum

出典と根拠

ORDレコード
ord-925df8772b744ebba43c47590e0cb8bb
出典データセット
uspto-grants-2014_09
特許番号
US08822430B2

関連ノート

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