(2R)-2-isobutylsuccinic acid → HCID 86593154、化合物
反応式
[CH2:1]([C@H:5]([CH2:9][C:10]([OH:12])=[O:11])[C:6]([OH:8])=O)[CH:2]([CH3:4])[CH3:3]>C(Cl)(=O)C>[CH2:1]([C@@H:5]1[CH2:9][C:10](=[O:11])[O:12][C:6]1=[O:8])[CH:2]([CH3:3])[CH3:4]参加物
3
実験手順
A solution of (2R)-2-isobutylsuccinic acid (35 mg, 0.2 mmol) in acetyl chloride (1.2 ml) was heated at reflux under nitrogen for 2.2 hours then volatile components removed by distillation in vacuo to leave (3R)-3-isobutyldihydrofuran-2,5-dione as an oily residue which was used without further purification.
後処理
- temperatureat reflux under nitrogen for 2.2 hours
- customvolatile components removed by distillation in vacuo
出典と根拠
- ORDレコード
- ord-fe312e0a60bb4905895e7ba0ec702844
- 出典データセット
- uspto-grants-2006_11
- 特許番号
- US07132449B2
反応ノート
読み込み中…