Malononitrile → N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide

HRID 720462

反応式

HRID 720462 の反応式
[NH:1]([C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3].[C:13](#[N:17])[CH2:14][C:15]#[N:16]>C(O)C.N1CCCCC1>[C:15]([C:14]([C:13]#[N:17])=[CH:9][C:8]1[CH:11]=[CH:12][C:5]([NH:1][C:2](=[O:3])[CH3:4])=[CH:6][CH:7]=1)#[N:16]

参加物

5

反応物 2

HCID 8010MalononitrileHCID 739424-Acetamidobenzaldehyde

生成物 1

HCID 33296N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide

試薬・触媒・溶媒 2

HCID 8082Piperidine触媒HCID 702Ethanol溶媒

実験手順

32.6 g (0.2 mol) of 4-acetaminobenzaldehyde and 13.74 g (0.208 mol) of malononitrile are initially charged in 140 ml of ethanol, and 24 drops of piperidine are added. The mixture is stirred at reflux for 30 min. After cooling, the crystals are filtered off with suction and dried.

後処理

  1. temperatureat reflux for 30 min
  2. temperatureAfter cooling
  3. filtrationthe crystals are filtered off with suction
  4. customdried

出典と根拠

ORDレコード
ord-cb0e9c695341411c89b66107140370ec
出典データセット
uspto-grants-2006_11
特許番号
US07135486B1

関連ノート

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