化工社化工社 化学情報印刷レポート · 研究参考用
3-(4-Methyl-1-piperazine)propan-1-ol → n-[(5s)-3-(3-(4-Methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5h-dibenzo[a,c]cyclohepten-5-yl]acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(4-Methyl-1-piperazine)propan-1-ol | HCID 79208 | — |
| 反応物 | N-Acetylcolchicinol | HCID 97865 | — |
| 生成物 | n-[(5s)-3-(3-(4-Methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5h-dibenzo[a,c]cyclohepten-5-yl]acetamide | HCID 9848717 | 22% |
反応手順
Using an analogous procedure to that described for Example 7, N-acetyl-colchicinol was reacted with 4-(3-hydroxypropyl)-1-methylpiperazine to give N-[(5S)-3-(3-(4-methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-5-yl]acetamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07135502B1 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-6dd86504269c4126a9a6f0039fa5a4eb |
| 出典メモ | uspto-grants-2006_11 |