Hydrochloric Acid → 412357-30-3

HRID 722017ノート

反応式

HRID 722017 の反応式
C(OC([N:8]1[CH2:13][CH2:12][C:11]([NH:17]C(OCC2C=CC=CC=2)=O)([CH2:14][O:15]C)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:28]>>[ClH:28].[ClH:28].[NH2:17][C:11]1([CH2:14][OH:15])[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 21882588HCID 21882588、化合物

生成物 1

HCID 21882556412357-30-3

実験手順

A mixture comprising 3.78 g of N-tert-butoxycarbonyl-4-benzyloxycarbonylamino-4-methoxymethylpiperidine (a compound obtained in Reference Example 6-3 (1)) and 38 ml of concentrated hydrochloric acid was refluxed for 3 days. The reaction mixture was concentrated and the residue was washed with tetrahydrofuran to obtain 2.8 g of 4-amino-4-hydroxymethylpiperidine dihydrochloride.

後処理

  1. temperaturewas refluxed for 3 days
  2. concentrationThe reaction mixture was concentrated
  3. washthe residue was washed with tetrahydrofuran

出典と根拠

ORDレコード
ord-5778dde5c57c4cc4b87e8385475cd296
出典データセット
uspto-grants-2006_11
特許番号
US07138397B2

反応ノート

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