O-Benzylhydroxylamine → N-(Benzyloxy)-9-(3-chloro-2,6-difluorobenzyl)-9H-beta-carboline-3-carboxamide
反応式
[Cl:1][C:2]1[C:3]([F:26])=[C:4]([C:22]([F:25])=[CH:23][CH:24]=1)[CH2:5][N:6]1[C:18]2[CH:17]=[N:16][C:15]([C:19]([OH:21])=O)=[CH:14][C:13]=2[C:12]2[C:7]1=[CH:8][CH:9]=[CH:10][CH:11]=2.[CH2:27]([O:34][NH2:35])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[CH2:27]([O:34][NH:35][C:19]([C:15]1[N:16]=[CH:17][C:18]2[N:6]([CH2:5][C:4]3[C:22]([F:25])=[CH:23][CH:24]=[C:2]([Cl:1])[C:3]=3[F:26])[C:7]3[C:12]([C:13]=2[CH:14]=1)=[CH:11][CH:10]=[CH:9][CH:8]=3)=[O:21])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1参加物
3
実験手順
The title compound is prepared by coupling of 9-(3-chloro-2,6-difluorobenzyl)-9H-β-carboline-3-carboxylic acid and O-benzyl hydroxyamine under conditions similar to those provided in step (b) of example 7.
後処理
- customthose provided in step (b) of example 7
出典と根拠
- ORDレコード
- ord-d364ee416b97446c9f5a5aafeeb128d7
- 出典データセット
- uspto-grants-2006_11
- 特許番号
- US07138408B2
反応ノート
読み込み中…