Methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate → 5-Cyclopentanecarbonyl-3-(2,2,2-trifluoroacetylamino)thiophene-2-carboxylic acid methyl ester

HRID 72217

反応式

HRID 72217 の反応式
[CH3:1][O:2][C:3]([C:5]1[S:6][CH:7]=[CH:8][C:9]=1[NH:10][C:11](=[O:16])[C:12]([F:15])([F:14])[F:13])=[O:4].COCN[C:21]([CH:23]1[CH2:27][CH2:26][CH2:25][CH2:24]1)=[O:22]>>[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([C:21]([CH:23]2[CH2:27][CH2:26][CH2:25][CH2:24]2)=[O:22])=[CH:8][C:9]=1[NH:10][C:11](=[O:16])[C:12]([F:13])([F:14])[F:15])=[O:4]

参加物

3

反応物 2

HCID 2805185Methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylateHCID 45084462Cyclopentanecarboxylic acid methoxymethylamide

生成物 1

HCID 866287855-Cyclopentanecarbonyl-3-(2,2,2-trifluoroacetylamino)thiophene-2-carboxylic acid methyl ester

実験手順

3-(2,2,2-Trifluoroacetylamino)thiophene-2-carboxylic acid methyl ester and cyclopentanecarboxylic acid methoxymethylamide were reacted by method M. The product with the molecular weight of 349.33 (C14H14F3NO4S) was obtained in this way; MS (ESI): 350 (M+H+).

後処理

  1. customThe product with the molecular weight of 349.33 (C14H14F3NO4S) was obtained in this way

出典と根拠

ORDレコード
ord-679a0478d72b48cab53acb33c9e08c05
出典データセット
uspto-grants-2014_09
特許番号
US08828991B2

関連ノート

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