5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-amine → 5-(2-Aminophenyl)-1,3,4-oxadiazol-2-amine

HRID 722219

反応式

HRID 722219 の反応式
[H][H].[N+:3]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[O:16][C:15]([NH2:17])=[N:14][N:13]=1)([O-])=O>>[NH2:3][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[O:16][C:15]([NH2:17])=[N:14][N:13]=1

参加物

3

反応物 2

HCID 7120425-(2-Nitrophenyl)-1,3,4-oxadiazol-2-amineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 50938855-(2-Aminophenyl)-1,3,4-oxadiazol-2-amine

実験手順

Hydrogen was introduced at atmospheric pressure into the solution of 350 mg of 5-(2-nitrophenyl)-[1,3,4]oxadiazol-2-ylamine until the theoretical amount had been taken up. After filtering off the catalyst with suction and concentrating the mixture under reduced pressure, the remaining oily residue was purified by column chromatography (solvent: 95:5 dichloromethane/methanol; silica gel).

後処理

  1. filtrationAfter filtering off the catalyst with suction
  2. concentrationconcentrating the mixture under reduced pressure
  3. customthe remaining oily residue was purified by column chromatography (solvent: 95:5 dichloromethane/methanol; silica gel)

出典と根拠

ORDレコード
ord-d726a4112522467aa7270fe17a87f474
出典データセット
uspto-grants-2006_11
特許番号
US07138414B2

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