Dimethylformamide → N,N,N'-trimethyl-N'-(4-nitrophenyl)-1,2-ethanediamine
反応式
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][NH:5][CH3:6].C(=O)([O-])[O-].[K+].[K+].[N+:14]([C:17]1[CH:22]=[CH:21][C:20](F)=[CH:19][CH:18]=1)([O-:16])=[O:15].CN(C)C=O>O>[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][N:5]([CH3:6])[C:20]1[CH:21]=[CH:22][C:17]([N+:14]([O-:16])=[O:15])=[CH:18][CH:19]=1参加物
6
実験手順
A mixture of N,N,N′-trimethylethane-1,2-diamine (2.17 g), potassium carbonate (3.0 g), 4-nitrofluorobenzene and dimethylformamide (30 ml) was stirred for 72 hours. The reaction mixture was diluted with water and extracted with ethyl acetate. The organic phase was washed with water and saturated brine, dried and concentrated. The product with the molecular weight of 223.28 (C11H17N3O2); MS (ESI): 224 ([M+H]+), was obtained in this way.
後処理
- extractionextracted with ethyl acetate
- washThe organic phase was washed with water and saturated brine
- customdried
- concentrationconcentrated
- customMS (ESI): 224 ([M+H]+), was obtained in this way
出典と根拠
- ORDレコード
- ord-d79caca2d30e429c984791767474afae
- 出典データセット
- uspto-grants-2006_11
- 特許番号
- US07141561B2
反応ノート
読み込み中…