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(Cyclopropylmethyl)methylamine → 1-(4-Cyclopentyloxyphenyl)-3-{4-[2-(cyclopropylmethyl(methyl)amino)-ethoxy]phenyl}-1,3-dihydroimidazol-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (Cyclopropylmethyl)methylamine | HCID 12919209 | — |
| 反応物 | 1-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one | HCID 21873330 | — |
| 生成物 | 1-(4-Cyclopentyloxyphenyl)-3-{4-[2-(cyclopropylmethyl(methyl)amino)-ethoxy]phenyl}-1,3-dihydroimidazol-2-one | HCID 21873315 | — |
反応手順
1-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one was reacted with cyclopropylmethyl(methyl)amine as described in example 5. The product with the molecular weight of 447.58 (C27H33N3O3); MS (ESI): 448 ([M+H]+) was obtained in this way.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07141561B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-22509260bd84463ea32860c5405bc0a4 |
| 出典メモ | uspto-grants-2006_11 |