1-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one → 2-(Acetylmethylamino)-N-{4-[2-oxo-3-(4-phenoxyphenyl)-2,3-dihydroimidazol-1-yl]phenyl}acetamide

HRID 723377

反応式

HRID 723377 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[CH:11][N:10]([C:13]3[CH:18]=[CH:17][C:16]([O:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)=[CH:15][CH:14]=3)[C:9]2=[O:26])=[CH:4][CH:3]=1.[C:27]([CH2:30][NH:31][CH2:32][C:33](O)=[O:34])(=[O:29])[CH3:28]>>[C:27]([CH2:30][NH:31][CH2:32][C:33]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH:12]=[CH:11][N:10]([C:13]3[CH:18]=[CH:17][C:16]([O:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)=[CH:15][CH:14]=3)[C:9]2=[O:26])=[CH:6][CH:7]=1)=[O:34])(=[O:29])[CH3:28]

参加物

3

反応物 2

HCID 102468281-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-oneHCID 21873483(Acetylmethylamino)acetic acid

生成物 1

HCID 218733352-(Acetylmethylamino)-N-{4-[2-oxo-3-(4-phenoxyphenyl)-2,3-dihydroimidazol-1-yl]phenyl}acetamide

実験手順

1-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one was reacted with (acetylmethylamino)acetic acid as described in example 217. The product with the molecular weight of 456.51 (C26H24N4O4); MS (ESI): 457 ([M+H] ) was obtained as hydrotrifluoroacetate in this way.

後処理

  1. customMS (ESI): 457 ([M+H] ) was obtained as hydrotrifluoroacetate in this way

出典と根拠

ORDレコード
ord-a230db8571f743bda696a9f6e38c50ca
出典データセット
uspto-grants-2006_11
特許番号
US07141561B2

関連ノート

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