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Trimethyl((tributylstannyl)ethynyl)silane → 2-(4-Hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trimethyl((tributylstannyl)ethynyl)silane | HCID 639663 | — |
| 反応物 | 4-Bromo-2-(4-hydroxyphenyl)quinolin-6-ol | HCID 135454802 | — |
| 生成物 | 2-(4-Hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-ol | HCID 135409783 | 83% |
反応手順
This compound was prepared from 6a and (trimethylsilylethynyl)tributyltin according to method J. Yellow powder; Yield: 83%; mp 210° C. (dec.); 1H-NMR (300 MHz, acetone-d6) δ 0.38 (s, 9H), 7.02 (d, J=8.7 Hz, 2H), 7.44 (dd, J=9.1, 2.7 Hz, 1H), 7.63 (d, J=2.7 Hz, 1H), 7.99 (d, J=9.1 Hz, 1H), 8.05 (s, 1H), 8.18 (d, J=8.7 Hz, 2H), 8.70 (s, 1H), 9.15 (s, 1H); MS (ESI) m/z 332 ([M−H]−), 334 ([M+H]+); Anal. Calcd for C20H19NO2Si: C: 72.04, H: 5.74, N: 4.20. Found: C: 71.67, H: 5.79, N: 4.07.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07084276B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-4c803b350ae34937859e5cb419f1475d |
| 出典メモ | uspto-grants-2006_08 |