反応式
CS([O:5][CH:6]1[CH2:9][N:8]([C:10]2[N:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:11]=2[C:12]([O:14][CH3:15])=[O:13])[CH2:7]1)(=O)=O.O[C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[N:26]=1>>[F:21][C:20]([F:23])([F:22])[C:17]1[CH:18]=[N:19][C:10]([N:8]2[CH2:9][CH:6]([O:5][C:25]3[CH:30]=[CH:29][CH:28]=[C:27]([C:31]([F:34])([F:33])[F:32])[N:26]=3)[CH2:7]2)=[C:11]([CH:16]=1)[C:12]([O:14][CH3:15])=[O:13]参加物
3
実験手順
The title compound (D89) (25 mg) was prepared according to the experimental procedure described in Description 88 starting from methyl 2-(3-((methylsulfonyl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinate (D68) (120 mg, 0.34 mmol) and 2-Hydroxy-6-(trifluoromethyl)pyridine (55.12 mg, 0.34 mmol, commercially available from Fluorochem#032990).
出典と根拠
- ORDレコード
- ord-711a64390e9f4475bb12ad8866e7a60d
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08828987B2
関連ノート
読み込み中…