化工社化工社 化学情報印刷レポート · 研究参考用
3-Fluorophenol → 5-Fluoro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Fluorophenol | HCID 9743 | — |
| 反応物 | Methyl 5-fluoro-2-(3-((methylsulfonyl)oxy)azetidin-1-yl)nicotinate | HCID 86697878 | — |
| 生成物 | 5-Fluoro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid | HCID 67958637 | 119.5% |
反応手順
The title compound (D132) (108 mg) was prepared according to the experimental procedure described in Description 115 starting from methyl 5-fluoro-2-(3-((methylsulfonyl)oxy)azetidin-1-yl)nicotinate (D71) (90 mg, 0.295 mmol) and 3-Fluorophenol (0.029 ml, 0.295 mmol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08828987B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-c613aafd2f95412e82b2c5be69c870a5 |
| 出典メモ | uspto-grants-2014_09 |