(Chlorothio)formyl chloride → 5-Methoxymethyl-1,3,4-oxathiazol-2-one
反応式
Cl[C:2]([S:4]Cl)=[O:3].[CH3:6][O:7][CH2:8][C:9]([NH2:11])=[O:10]>C1(C)C=CC=CC=1>[CH3:6][O:7][CH2:8][C:9]1[O:10][C:2](=[O:3])[S:4][N:11]=1参加物
4
実験手順
Chlorocarbonylsulfenyl chloride (7.35 g) was added to a suspension of methoxyacetamide (5 g) in toluene (30 cm3). The reaction mixture was stirred and heated at 90°-100° C. for 5 hours, then cooled. The solvent was removed by evaporation under reduced pressure to give a brown gum (6.6 g). M+ =147; 1H NMR (DMSO-d6): δ 3.30(3H,s); 4.30(2H,s) which was used in the next step without further purification.
後処理
- temperatureheated at 90°-100° C. for 5 hours
- temperaturecooled
- customThe solvent was removed by evaporation under reduced pressure
出典と根拠
- ORDレコード
- ord-a9cb3bb7f0054aea9a106e2756276237
- 出典データセット
- uspto-grants-1998_01
- 特許番号
- US05705516
反応ノート
読み込み中…