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(R)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate → HCID 67958687、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate | HCID 22857708 | — |
| 反応物 | Methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate | HCID 86697873 | — |
| 生成物 | HCID 67958687 | HCID 67958687 | 90.3% |
反応手順
The title compound (D201) (80 mg) was prepared according to the experimental procedure described in Description 160 starting from (R)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate (D42) (100 mg, 0.338 mmol) and reacting in the second step with methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate (D97) (61.8 mg, 0.169 mmol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08828987B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-efbfd4fe022b42dea58474f74f96b715 |
| 出典メモ | uspto-grants-2014_09 |