1-Naphthalenesulfonyl chloride → alpha-Naphthyl-p-methylphenyldisulfone

HRID 725718ノート

反応式

HRID 725718 の反応式
[OH2:1].[OH2:2].[C:3]1([CH3:12])[CH:8]=[CH:7][C:6]([S:9]([O-:11])=[O:10])=[CH:5][CH:4]=1.[Na+].[C:14]1(S(Cl)(=O)=O)[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1>O>[C:22]1([C:5]2[CH:4]=[C:3]([CH3:12])[CH:8]=[CH:7][C:6]=2[S:9](=[O:11])(=[O:10])[S:9]([C:6]2[CH:7]=[CH:8][C:3]([CH3:12])=[CH:4][C:5]=2[C:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:17]=[CH:16][CH:15]=2)(=[O:2])=[O:1])[C:23]2[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:19]=[CH:20][CH:21]=1

参加物

4

反応物 2

HCID 665601-Naphthalenesulfonyl chlorideHCID 23678556Sodium toluene-4-sulphinate dihydrate

生成物 1

HCID 86751875alpha-Naphthyl-p-methylphenyldisulfone収率 46.3%

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

11.8 g of sodium p-toluenesulfinate dihydrate were dissolved in 20 ml of water, and 11.3 g of α-naphthalenesulfonic acid chloride were added thereto and reacted for 24 hours at room temperature while stirring. 250 ml of water were added thereto, the precipitate formed were taken out by filtration, and this was recrystallized from a mixed solvent comprising benzene and ethanol. Thus, 6.5 g of α-naphthyl-p-methylphenyldisulfone (PAG 5-6) were obtained.

後処理

  1. customreacted for 24 hours at room temperature
  2. customthe precipitate formed
  3. filtrationwere taken out by filtration
  4. customthis was recrystallized from a mixed solvent comprising benzene and ethanol

出典と根拠

ORDレコード
ord-d8a76e65b386458598b62f89ec27914a
出典データセット
uspto-grants-1998_01
特許番号
US05707776

反応ノート

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