関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hexane | HCID 8058 | — |
| 反応物 | Ammonium Chloride | HCID 25517 | — |
| 反応物 | Citral | HCID 638011 | — |
| 反応物 | HCID 178418332 | HCID 178418332 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | tert-Butyl methyl ether | HCID 15413 | — |
| 生成物 | 4,8-Dimethylnona-3,7-dien-2-ol | HCID 106874 | — |
反応手順
1 l of t-butyl methyl ether and 1.05 l of 3N methyl magnesium chloride solution were placed under N2 in a 41/2 l sulphonation flask having a thermometer, stirrer and dropping funnel and 456 g of geranial in 500 ml of t-butyl methyl ether were added dropwise at 0° C. The mixture was stirred at 10° C. for 1 hour and poured on to 3 kg of ice and 500 g of NH4Cl and treated with 1 l of hexane. After mixing well the H2O phase was separated and washed neutral 3 times with 500 ml of NH4Cl solution, dried and evaporated.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05707961 |
|---|
| 出典データセット | uspto-grants-1998_01 |
|---|
| ORD ID | ord-f339ef21ee2f4548b11a6ee422594f82 |
|---|
| 出典メモ | uspto-grants-1998_01 |
|---|
