Acetic Acid → Benzenemethanol, 4-nitro-, 1-acetate

HRID 726480

反応式

HRID 726480 の反応式
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8][OH:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:12](OC(=O)C)(=[O:14])[CH3:13].C(O)(=O)C>O>[C:12]([O:9][CH2:8][C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:11][CH:10]=1)(=[O:14])[CH3:13]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 7918Acetic AnhydrideHCID 692754-Nitrobenzyl alcohol

生成物 1

HCID 12094Benzenemethanol, 4-nitro-, 1-acetate

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

7.6 g (0.05 mol) of 4-nitrobenzyl alcohol, 4.7 ml (0.05 mol) of acetic anhydride and 5.8 ml (0.1 mol) of acetic acid were introduced into a round-bottomed flask and the mixture was heated at reflux for eight hours. The reaction medium was poured into water, extracted with ethyl ether, the organic phase decanted off, dried over magnesium sulfate and evaporated. The residue was triturated in hexane, filtered and dried. 6.1 g (62%) of 4-nitrobenzyl acetate of melting point 77°-78° C. were recovered.

後処理

  1. temperaturethe mixture was heated
  2. temperatureat reflux for eight hours
  3. extractionextracted with ethyl ether
  4. customthe organic phase decanted off
  5. dry with materialdried over magnesium sulfate
  6. customevaporated
  7. customThe residue was triturated in hexane
  8. filtrationfiltered
  9. customdried
  10. custom6.1 g (62%) of 4-nitrobenzyl acetate of melting point 77°-78° C. were recovered

出典と根拠

ORDレコード
ord-688eb585bdcb494e85d1a56d24f7b9a6
出典データセット
uspto-grants-1998_01
特許番号
US05709867

関連ノート

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