4-Chloro-N-methylbenzenamine → 4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazole
反応式
[NH:1]1[CH:5]=[C:4]([S:6](Cl)(=[O:8])=[O:7])[N:3]=[CH:2]1.[Cl:10][C:11]1[CH:18]=[CH:17][C:14]([NH:15][CH3:16])=[CH:13][CH:12]=1>>[Cl:10][C:11]1[CH:18]=[CH:17][C:14]([N:15]([CH3:16])[S:6]([C:4]2[N:3]=[CH:2][NH:1][CH:5]=2)(=[O:8])=[O:7])=[CH:13][CH:12]=1参加物
3
実験手順
Imidazole-4-sulphonyl chloride was reacted with 4-chloro-N-methylaniline to give 4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazole, m.p. 217°-9°. This was then treated with dimethylsulphamoyl chloride in a similar manner to that described in Example 1, to give 1-dimethylsulphamoyl-4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazole, m.p. 131.5°-132°.
出典と根拠
- ORDレコード
- ord-3e96b47044874731acf046e5f4959f64
- 出典データセット
- uspto-grants-1991_09
- 特許番号
- US05045557
反応ノート
読み込み中…