Hydrochloric Acid → 4-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride

HRID 727843ノート

反応式

HRID 727843 の反応式
[N:1]1([CH:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1.[ClH:19]>C(O)C>[ClH:19].[N:1]1([CH:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 145143684-[1-(1-Imidazolyl)-butyl]-benzoic acid

生成物 1

HCID 145143694-[1-(1-Imidazolyl)-butyl]-benzoic acid, hydrochloride

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1.0 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid is dissolved in 20 ml of ethanol and mixed with 10 ml of concentrated hydrochloric acid. The reaction mixture is precipitated into 100 ml of water and the precipitate is suctioned off. After recrystallization from ethanol, 0.95 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride with a melting point of 38° C. is obtained.

後処理

  1. customThe reaction mixture is precipitated into 100 ml of water
  2. customAfter recrystallization from ethanol, 0.95 g of 4-[1-(1-imidazolyl)-butyl]-benzoic acid, hydrochloride with a melting point of 38° C.
  3. customis obtained

出典と根拠

ORDレコード
ord-fc283fd46dc345c19663bdc84467f22e
出典データセット
uspto-grants-1991_09
特許番号
US05045558

反応ノート

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