1-[4-[1-(1-Imidazolyl)-butyl]-phenyl]-ethanol → 4'-[1-(1-Imidazolyl)-butyl]-acetophenone
反応式
[N:1]1([CH:6]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([OH:18])[CH3:17])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[N:1]1([CH:6]([C:10]2[CH:11]=[CH:12][C:13]([C:16](=[O:18])[CH3:17])=[CH:14][CH:15]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1参加物
4
実験手順
200 mg of the alcohol of example 7 is stirred in 10 ml of methylene chloride with 1 g of manganese dioxide overnight. It is suctioned off, concentrated by evaporation and the residue is distilled at 180° C./0.03 hPa. 100 mg of the title compound is obtained as colorless oil.
後処理
- concentrationconcentrated by evaporation
- distillationthe residue is distilled at 180° C./0.03 hPa
出典と根拠
- ORDレコード
- ord-68934ef1a08b4ddeaccceb3e340fedc0
- 出典データセット
- uspto-grants-1991_09
- 特許番号
- US05045558
反応ノート
読み込み中…