L-Gulose → Anhydro-d-mannosan

HRID 728206ノート

反応式

HRID 728206 の反応式
O=[CH:2][C@H:3]([C@H:5]([C@@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4]>O>[C@@H:11]12[O:12][CH2:2][C@H:3]([O:4]1)[C@@H:5]([OH:6])[C@H:7]([OH:8])[C@@H:9]2[OH:10]

参加物

3

反応物 1

HCID 80127L-Gulose

生成物 1

HCID 11947765Anhydro-d-mannosan

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Syrupy L-gulose was heated on a steam bath in water with strong acid resin (Dowex 50 W-X8, H+ form) for 64 h. The solution was then filtered, the resin washed with water, and the combined filtrate was passed onto a column packed with strong base resin (Amberlite IRA-900, OH- form). The column was washed with distilled water to elute the title compound which crystallized from ethanol. Recrystallized from ethanol it has mp 155.5°-156.5° C. The column was then immediately washed with aqueous acetic acid (M) to elute unreacted L-gulose which was recycled to provide further title compound.

後処理

  1. filtrationThe solution was then filtered
  2. washthe resin washed with water
  3. washThe column was washed with distilled water
  4. washto elute the title compound which
  5. customcrystallized from ethanol
  6. customRecrystallized from ethanol it
  7. washThe column was then immediately washed with aqueous acetic acid (M)
  8. washto elute unreacted L-gulose which

出典と根拠

ORDレコード
ord-7071e9fa7c1e442a8c0394816aa747f6
出典データセット
uspto-grants-1991_09
特許番号
US05047518

反応ノート

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