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Hydrochloric Acid → N-tosyl-bis(2-tosyloxy propyl) amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 反応物 | Diisopropanolamine | HCID 8086 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | N-tosyl-bis(2-tosyloxy propyl) amine | HCID 17769785 | — |
反応手順
A solution of 53.2 g (0.4 mole) of diiso-propanolamine in 50 cm3 of pyridine is added dropwise with cooling to a solution of 248 g (1.3 mole) of tosyl chloride in 200 cm3 of pyridine at 0° C. so that the temperature is maintained between 0° and 5° C. The mixture is left at this temperature for 72 h. It is then poured into 2 l of water plus ice and 250 cm3 of concentrated hydrochloric acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05049667 |
| 出典データセット | uspto-grants-1991_09 |
| ORD ID | ord-96d9d9e990a04f49bfd810ca007ce619 |
| 出典メモ | uspto-grants-1991_09 |