Hydrochloric Acid → HCID 88508788、化合物
反応式
[NH2:1][CH:2](/[CH:6]=[CH:7]/[CH2:8][P:9]([OH:12])([OH:11])=[O:10])[C:3]([OH:5])=[O:4].Cl>C(O)(CC)C>[CH:2]([O:4][C:3](=[O:5])[CH:2]([NH2:1])/[CH:6]=[CH:7]/[CH2:8][P:9]([OH:12])([OH:11])=[O:10])([CH2:6][CH3:7])[CH3:3]参加物
4
実験手順
1.5 g of E-2-amino-5-phosphono-3-pentenoic acid are suspended in 30 ml of sec.-butanol and the suspension is saturated with hydrogen chloride gasfor 4 hours at 75°. After concentration, the residue is dissolved in10 ml of 2-butanol, 10 ml of propylene oxide are added and the precipitate is filtered off. Recrystallisation from water/acetone 1:1 yields E-2-amino-5-phosphono-3-pentenoic acid sec.-butyl ester, m.p. 169°-170°.
後処理
- concentrationAfter concentration
- dissolutionthe residue is dissolved in10 ml of 2-butanol, 10 ml of propylene oxide
- additionare added
- filtrationthe precipitate is filtered off
- customRecrystallisation from water/acetone 1:1
出典と根拠
- ORDレコード
- ord-25f41809885c4005b7cbd71475cdd198
- 出典データセット
- uspto-grants-1991_09
- 特許番号
- US05051413
反応ノート
読み込み中…