化工社化工社 化学情報印刷レポート · 研究参考用
Boron tribromide → 4-Bromocatechol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Boron tribromide | HCID 25134 | — |
| 反応物 | Benzene, 4-bromo-1,2-dimethoxy- | HCID 76114 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-Bromocatechol | HCID 28487 | 96.1% |
反応手順
6.51 g (0.0300 mol) of 4-bromoveratrole is dissolved in 50 ml of dichloromethane. To this suspension is added 37.6 g (0.150 mol) of boron tribromide at 0° C. The mixture was stirred for 3 hours at room temperature. Solvents were removed under reduced pressure. The resulting brown oil was dissolved in ethyl acetate and filtered through a pad of silica gel. The filtrate was concentrated to afford 5.45 g of 4-bromo catechol as a light brown oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07582637B2 |
| 出典データセット | uspto-grants-2009_09 |
| ORD ID | ord-a93b7e37498b498d9f1c912a40155f65 |
| 出典メモ | uspto-grants-2009_09 |