4-Fluorobenzoic Acid → Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate

HRID 729882

反応式

HRID 729882 の反応式
O=C(C1SC=CC=1)CC(OCC)=O.S1C=CC=C1C1C=CN=C(N)N=1.C[C:27]1([CH3:35])[O:32][C:31](=[O:33])[CH2:30][C:29](=[O:34])O1.[F:36][C:37]1[CH:45]=[CH:44][C:40](C(O)=O)=[CH:39][CH:38]=1>>[F:36][C:37]1[CH:45]=[CH:44][C:40]([C:29](=[O:34])[CH2:30][C:31]([O:32][CH2:27][CH3:35])=[O:33])=[CH:39][CH:38]=1

参加物

5

反応物 4

HCID 99734-Fluorobenzoic AcidHCID 162492,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 255159Ethyl 3-oxo-3-(thiophen-2-yl)propanoateHCID 27644074-(Thiophen-2-yl)pyrimidin-2-amine

生成物 1

HCID 2758844Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate

実験手順

This material is prepared by a method analogous to that described for preparation of ethyl 3-oxo-3-(2-thienyl)propanoate in preparation of 1D, starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and 4-fluorobenzoic acid.

後処理

  1. customThis material is prepared by a method analogous to

出典と根拠

ORDレコード
ord-e72368ad169846ec9c758bd4d1058246
出典データセット
uspto-grants-2009_09
特許番号
US07582645B2

関連ノート

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