Triethylamine → 1-Benzyl-5-oxopyrrolidine-3-carboaldehyde

HRID 732669ノート

反応式

HRID 732669 の反応式
C(N(CC)CC)C.[CH2:8]([N:15]1[CH2:19][CH:18]([CH2:20][OH:21])[CH2:17][C:16]1=[O:22])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>CS(C)=O>[CH2:8]([N:15]1[C:16](=[O:22])[CH2:17][CH:18]([CH:20]=[O:21])[CH2:19]1)[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

参加物

4

反応物 2

HCID 8471TriethylamineHCID 1788241-Benzyl-4-(hydroxymethyl)pyrrolidin-2-one

生成物 1

HCID 722996181-Benzyl-5-oxopyrrolidine-3-carboaldehyde

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

実験手順

Triethylamine and a pyridine-sulfur trioxide complex were added to a DMSO solution of 1-benzyl-4-(hydroxymethyl)pyrrolidin-2-one and stirred at room temperature for 2Hours. Thereafter, its work-up and purification were carried out in the standard method to obtain 1-benzyl-5-oxopyrrolidine-3-carboaldehyde. EI: 203.

後処理

  1. customThereafter, its work-up and purification

出典と根拠

ORDレコード
ord-06587b7bb10048a493338260c3185964
出典データセット
uspto-grants-2009_09
特許番号
US07585886B2

反応ノート

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