5-methoxy-9-oxo-9H-xanthene-3-carboxylic acid → 5-Bromo-N,N-diethyl-9-oxo-9H-xanthene-3-carboxamide
反応式
[Br:1][C:2]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:3]=1[O:4][C:5]1[CH:6]=[C:7]([C:17](O)=[O:18])[CH:8]=[CH:9][C:10]=1[C:11]2=[O:16].COC1C=CC=C2C=1OC1C=C(C(O)=O)C=CC=1C2=O.[CH2:40]([N:42](CC)[C:43]([C:45]1C=CC2CC3C(OC=2C=1)=CC=CC=3)=O)[CH3:41]>>[CH2:40]([N:42]([CH2:43][CH3:45])[C:17]([C:7]1[CH:8]=[CH:9][C:10]2[C:11](=[O:16])[C:12]3[C:3]([O:4][C:5]=2[CH:6]=1)=[C:2]([Br:1])[CH:15]=[CH:14][CH:13]=3)=[O:18])[CH3:41]参加物
4
実験手順
Using an adaptation of the method described in Procedure 16, substituting 5-bromo-9-oxo-9H-xanthene-3-carboxylic acid, 3d for 5-methoxy-9-oxo-9H-xanthene-3-carboxylic acid, 3c, title compound 5-bromo-9-oxo&9H-xanthene-3-carboxylic acid diethylamide, 4d was obtained. MS m/z (MH+) 374/375.8.