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Vinyltrimethylsilane → 5-Bromo-1,3-dimethyl-2-vinylbenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Vinyltrimethylsilane | HCID 79102 | — |
| 反応物 | 5-Bromo-2-iodo-1,3-dimethylbenzene | HCID 2735573 | — |
| 反応物 | 4-Bromo-2-methyl-1-vinylbenzene | HCID 22598656 | — |
| 生成物 | 5-Bromo-1,3-dimethyl-2-vinylbenzene | HCID 53418364 | 94% |
反応手順
Using a procedure analogous to that used to prepare 30A, 5-bromo-2-iodo-1,3-dimethylbenzene (15.6 g, 48 mmol) was reacted with trimethyl(vinyl)silane in a pressure vessel at 160° C. for 1 h to yield 32A (10.0 g, 94%) as a clear oil. 1H NMR (400 MHz, CDCl3) δ ppm 2.26 (s, 6 H) 5.24 (dd, J=17.86, 1.92 Hz, 1 H) 5.55 (dd, J=11.54, 2.20 Hz, 1 H) 7.18 (s, 2 H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07592331B2 |
| 出典データセット | uspto-grants-2009_09 |
| ORD ID | ord-d31eb0f913b94621abadbcd058495c2e |
| 出典メモ | uspto-grants-2009_09 |