2-(4-Bromophenyl)propan-1-ol → 4-Bromo-beta,beta-dimethylbenzeneethanol

反応式

BrC1C=CC(C(C)CO)=CC=1.[Br:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]([CH3:25])([CH3:24])[C:20](OC)=[O:21])=[CH:15][CH:14]=1>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([C:19]([CH3:25])([CH3:24])[CH2:20][OH:21])=[CH:17][CH:18]=1

参加物

反応物 2

HCID 5690622-(4-Bromophenyl)propan-1-ol

HCID 3651431Methyl 2-(4-bromophenyl)-2-methylpropanoate

生成物 1

HCID 128051244-Bromo-beta,beta-dimethylbenzeneethanol収率 100.8%

実験手順

According to the procedure for the preparation of 73B, methyl 2-(4-bromophenyl)-2-methylpropanoate (2.15 g, 8.36 mmol) afforded 1.93 g of 74A as a colorless oil. MS (ESI) m/z 211.1 (M-OH)+.

出典と根拠

ORDレコード: ord-d002505946eb4e2ab8384f36403a873c
出典データセット: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07592331B2

反応ノート

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