4-Methyl-3-nitrobenzenesulfonyl chloride → 3-(4-Methyl-3-nitrobenzenesulfonyl)-1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylic acid ethyl ester

HRID 736113ノート

反応式

HRID 736113 の反応式
[CH2:1]([O:3][C:4]([C:6]1[C:12]2[NH:13][C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][C:19]=3[C:11]=2[CH2:10][CH2:9][NH:8][CH:7]=1)=[O:5])[CH3:2].[CH3:20][C:21]1[CH:26]=[CH:25][C:24]([S:27](Cl)(=[O:29])=[O:28])=[CH:23][C:22]=1[N+:31]([O-:33])=[O:32]>>[CH2:1]([O:3][C:4]([C:6]1[C:12]2[NH:13][C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][C:19]=3[C:11]=2[CH2:10][CH2:9][N:8]([S:27]([C:24]2[CH:25]=[CH:26][C:21]([CH3:20])=[C:22]([N+:31]([O-:33])=[O:32])[CH:23]=2)(=[O:28])=[O:29])[CH:7]=1)=[O:5])[CH3:2]

参加物

3

反応物 2

HCID 5606384-Methyl-3-nitrobenzenesulfonyl chlorideHCID 57467979Ethyl 1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylate

生成物 1

HCID 575591573-(4-Methyl-3-nitrobenzenesulfonyl)-1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylic acid ethyl ester

実験手順

The title compound was prepared in a manner similar to that described in Example 70 by using ethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate and 4-methyl-3-nitrobenzenesulfonyl chloride (˜3.4mg); MS (ES): 456 (MH+).

出典と根拠

ORDレコード
ord-be6f64ac271a47f6bacf8170ac85105b
出典データセット
uspto-grants-2009_09
特許番号
US07595311B2

反応ノート

読み込み中…