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HRID 736222作成日：2026年10月26日

Morpholine → 3-Fluoro-N-methyl-4-morpholin-4-yl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamide

https://huagongshe.com/reaction/736222

反応式

関与物質

役割名称HCID仕込み量
反応物MorpholineHCID 8083—
反応物3,4-Difluoro-N-methyl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamideHCID 59793564—
生成物3-Fluoro-N-methyl-4-morpholin-4-yl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamideHCID 68844164—

反応手順

The title compound was prepared according to the procedure described for example 202 from 3,4-Difluoro-N-methyl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamide (example CC) and morpholine to yield the title compound as a colourless foam, MS (m/e): 531.1 (M+H, 100%).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07595314B2
出典データセットuspto-grants-2009_09
ORD IDord-77f36718b5314807a88821ba34a56eed
出典メモuspto-grants-2009_09