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1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one → (3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one | HCID 567033 | — |
| 反応物 | 3-Nitrophenylguanidine Nitrate | HCID 178512513 | — |
| 生成物 | (3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine | HCID 9860872 | 69.7% |
反応手順
3-Nitrophenyl-guanidine nitrate (28 g, 0.12 mol) and 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one (16.9 g, 0.09 mol) were reacted according to the same procedure as Step 1.3 of Preparation 1 to give N-(3-nitrophenyl)-4-(3-pyridyl)-2-pyrimidine-amine (18.4 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07595323B2 |
| 出典データセット | uspto-grants-2009_09 |
| ORD ID | ord-18ee62cb361345d79978b33f89b667b2 |
| 出典メモ | uspto-grants-2009_09 |