Allyl isocyanate → 3-Oxo-3H-benzo[d]isothiazole-2-carboxylic acid allylamide

関与物質

反応手順

Following the synthetic procedure of 6a as described in Example 1, compound 6c (67% yield) was synthesized from benzo[d]isothiazol-3-one and allyl isocyanate as a white solid. mp 116-119° C.; IR(CHCl3) 3290, 1711, 1664, 1537 cm−1; 1H-NMR (CDCl3) δ 4.05-4.10 (m, 2H), 5.18-5.34 (m, 2H), 5.83-5.99 (m, 1H), 7.43 (t, J=7.2 Hz, 1H), 7.58 (d, J=7.2 Hz, 1H), 7.70 (t, J=7.2 Hz, 1H), 8.02 (d, J=7.2 Hz, 1H), 8.99 (br s, 1H); ESIMS m/e 235 (M++1).

情報源と証拠