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Iodoethane → HCID 86607915、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodoethane | HCID 6340 | — |
| 反応物 | Methyl cyclopent-1-ene-1-carboxylate | HCID 549129 | — |
| 反応物 | (+)-Benzylphenethylamine | HCID 1268086 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 生成物 | HCID 86607915 | HCID 86607915 | — |
反応手順
According to the procedure of Example 53, Step 1, using (R)-N-benzyl-N-α-methylbenzylamine (4.2 mL, 4.24 g, 20 mmol), n-butyllithium (2.4 M, 7.4 mL), methyl 1-cyclopentene-1-carboxylate (1.3 mL, 1.29 g, 10.2 mmol), and iodoethane (1.6 mL, 3.12 g, 20 mmol), methyl (1S,2R)-2-amino-1-ethylcyclopentanecarboxylate was obtained as a mixture of two components (1.103 g) after purification on silica gel, eluting with 2% ethyl acetate/hexanes.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07595327B2 |
| 出典データセット | uspto-grants-2009_09 |
| ORD ID | ord-d7b5ccc4a5f24e288786848fc76d7ae0 |
| 出典メモ | uspto-grants-2009_09 |